Rabbit Muscle Adenosine 5'-Monophosphate Aminohydrolase
نویسندگان
چکیده
منابع مشابه
Studies on the adenosine 3',5'-monophosphate-dependent protein kinases of rabbit skeletal muscle.
The adenosine 3’,5’-monophosphate-dependent (CAMPdependent) protein kinases of rabbit skeletal muscle have been partially characterized in terms of molecular size and subunit composition. Three and possibly four species of protein kinase have been detected. The largest form of the enzyme was estimated by gel filtration and sedimentation to have a molecular weight of 123,000 and to be made up of...
متن کاملPurification and properties of rabbit skeletal muscle adenosine 3',5'-monophosphate-dependent protein kinases.
A modified procedure for purification of the adenosine 3’,5’-monophosphate-dependent (cyclic AMP-dependent) protein kinase from rabbit skeletal muscle is described. This procedure results in the separation of the enzyme into two peaks of activity on diethylaminoethylcellulose. No interconversion of these two peaks was observed. Both peaks exhibit dependence on cyclic AMP, but under certain cond...
متن کاملAffinity labeling of the adenosine 5'-monophosphate binding site of rabbit muscle glycogen phosphorylase b with an adenosine 5'-monophosphate-cobalt(3) complex.
A new affinity labeling method is presented which may be used for enzyme-catalyzing reactions in the presence of magnesium. This method uses the substrate-cobalt(III) analog of the substrate-magnesium complex as a covalent label of the active site. The specific case of rabbit muscle glycogen phosphorylase b, which has been covalently labeled with a AMP-Co(II1) derivative at the allosteric site,...
متن کاملRenal Effects of Adenosine 3 ' , 5 ' - Cyclic Monophosphate and Dibutyryl Adenosine 3 , 5 ' - Cyclic Monophosphate
An abstract of this work appeared in 1970 Abstracts, The American Society of Nephrology. Received for publication 27 October 1970 and in revised form 28 January 1971. similar to the effect of renal arterial infusion of isoproterenol. The results suggest that synthesis of cyclic AMP in proximal renal tubule cells in response to stimulation of beta adrenergic or other receptors can mediate a decr...
متن کاملEffects of adenosine 5'-monophosphate and adenosine 3',5'-cyclic monophosphate on l cells.
The adenine nucleotides, 5'-AMP and 3',5'-cyclic AMP block L cells in the S-phase of the cell cycle. The intracellular level of cyclic AMP is reduced after incubation of cells with 5'-AMP, and rates of uridine transport are increased after incubation with either 5'-AMP or cyclic AMP. On the contrary, cyclic AMP levels are increased and uridine transport decreased in cells treated with an inhibi...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1971
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)77205-6